Atlas to Image With Tumor Registration Based on Demons and Deformation Inpainting

Abstract

This paper presents a method for nonlinear registration of images, where there exists no one-to-one correspondence in parts of the image. Such a situation occurs for instance in the case where an atlas of normal anatomy shall be matched to pathological data, such as tumors, resections or lesions. Our idea is to use local confidence weights and to model pathological regions with zero confidence. We integrate this concept into the efficient and publicly available diffeomorphic demons registration framework. Finally, we show that this process better captures deformations in high-confidence regions than without using the proposed modification. Furthermore, it is easy to implement and runs faster than previous approaches.

Publication
The MIDAS Journal - Computational Imaging Biomarkers for Tumors (CIBT) (2010)
Hans Lamecker
Hans Lamecker
Managing Director

Advancing 3D analysis, planning, design and manufacturing using innovative computational methodologies and tools.

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